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A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia

Placental trophoblasts (TBs) invade and remodel uterine vessels with an arterial bias. This process, which involves vascular mimicry, re-routes maternal blood to the placenta, but fails in pre-eclampsia. We investigated Notch family members in both contexts, as they play important roles in arterial...

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Bibliografische gegevens
Hoofdauteurs: Hunkapiller, Nathan M., Gasperowicz, Malgorzata, Kapidzic, Mirhan, Plaks, Vicki, Maltepe, Emin, Kitajewski, Jan, Cross, Jay C., Fisher, Susan J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Company of Biologists 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119307/
https://ncbi.nlm.nih.gov/pubmed/21693515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066589
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