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A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia
Placental trophoblasts (TBs) invade and remodel uterine vessels with an arterial bias. This process, which involves vascular mimicry, re-routes maternal blood to the placenta, but fails in pre-eclampsia. We investigated Notch family members in both contexts, as they play important roles in arterial...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119307/ https://ncbi.nlm.nih.gov/pubmed/21693515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066589 |
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