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Large-scale association analyses identifies 13 new susceptibility loci for coronary artery disease

We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 cases and 64,762 controls of European descent, followed by genotyping of top association signals in 60,738 additional individuals. This genomic analysis identified 13 novel loci harb...

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Detalhes bibliográficos
Main Authors: Schunkert, Heribert, König, Inke R., Kathiresan, Sekar, Reilly, Muredach P., Assimes, Themistocles L., Holm, Hilma, Preuss, Michael, Stewart, Alexandre F. R., Barbalic, Maja, Gieger, Christian, Absher, Devin, Aherrahrou, Zouhair, Allayee, Hooman, Altshuler, David, Anand, Sonia S., Andersen, Karl, Anderson, Jeffrey L., Ardissino, Diego, Ball, Stephen G., Balmforth, Anthony J., Barnes, Timothy A., Becker, Diane M., Becker, Lewis C., Berger, Klaus, Bis, Joshua C., Boekholdt, S. Matthijs, Boerwinkle, Eric, Braund, Peter S., Brown, Morris J., Burnett, Mary Susan, Buysschaert, Ian, Carlquist, Cardiogenics, John F., Chen, Li, Cichon, Sven, Codd, Veryan, Davies, Robert W., Dedoussis, George, Dehghan, Abbas, Demissie, Serkalem, Devaney, Joseph M., Do, Ron, Doering, Angela, Eifert, Sandra, El Mokhtari, Nour Eddine, Ellis, Stephen G., Elosua, Roberto, Engert, James C., Epstein, Stephen E., Faire, Ulf de, Fischer, Marcus, Folsom, Aaron R., Freyer, Jennifer, Gigante, Bruna, Girelli, Domenico, Gretarsdottir, Solveig, Gudnason, Vilmundur, Gulcher, Jeffrey R., Halperin, Eran, Hammond, Naomi, Hazen, Stanley L., Hofman, Albert, Horne, Benjamin D., Illig, Thomas, Iribarren, Carlos, Jones, Gregory T., Jukema, J.Wouter, Kaiser, Michael A., Kaplan, Lee M., Kastelein, John J.P., Khaw, Kay-Tee, Knowles, Joshua W., Kolovou, Genovefa, Kong, Augustine, Laaksonen, Reijo, Lambrechts, Diether, Leander, Karin, Lettre, Guillaume, Li, Mingyao, Lieb, Wolfgang, Linsel-Nitschke, Patrick, Loley, Christina, Lotery, Andrew J., Mannucci, Pier M., Maouche, Seraya, Martinelli, Nicola, McKeown, Pascal P., Meisinger, Christa, Meitinger, Thomas, Melander, Olle, Merlini, Pier Angelica, Mooser, Vincent, Morgan, Thomas, Mühleisen, Thomas W., Muhlestein, Joseph B., Münzel, Thomas, Musunuru, Kiran, Nahrstaedt, Janja, Nelson, Christopher P., Nöthen, Markus M., Olivieri, Oliviero, Patel, Riyaz S., Patterson, Chris C., Peters, Annette, Peyvandi, Flora, Qu, Liming, Quyyumi, Arshed A., Rader, Daniel J., Rallidis, Loukianos S., Rice, Catherine, Rosendaal, Frits R., Rubin, Diana, Salomaa, Veikko, Sampietro, M. Lourdes, Sandhu, Manj S., Schadt, Eric, Schäfer, Arne, Schillert, Arne, Schreiber, Stefan, Schrezenmeir, Jürgen, Schwartz, Stephen M., Siscovick, David S., Sivananthan, Mohan, Sivapalaratnam, Suthesh, Smith, Albert, Smith, Tamara B., Snoep, Jaapjan D., Soranzo, Nicole, Spertus, John A., Stark, Klaus, Stirrups, Kathy, Stoll, Monika, Tang, W. H. Wilson, Tennstedt, Stephanie, Thorgeirsson, Gudmundur, Thorleifsson, Gudmar, Tomaszewski, Maciej, Uitterlinden, Andre G., van Rij, Andre M., Voight, Benjamin F., Wareham, Nick J., Wells, George A., Wichmann, H.-Erich, Wild, Philipp S., Willenborg, Christina, Witteman, Jaqueline C. M., Wright, Benjamin J., Ye, Shu, Zeller, Tanja, Ziegler, Andreas, Cambien, Francois, Goodall, Alison H., Cupples, L. Adrienne, Quertermous, Thomas, März, Winfried, Hengstenberg, Christian, Blankenberg, Stefan, Ouwehand, Willem H., Hall, Alistair S., Deloukas, Panos, Thompson, John R., Stefansson, Kari, Roberts, Robert, Thorsteinsdottir, Unnur, O’Donnell, Christopher J., McPherson, Ruth, Erdmann, Jeanette, Samani, Nilesh J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119261/
https://ncbi.nlm.nih.gov/pubmed/21378990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.784
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