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Coupled ATP and potassium efflux from intercalated cells

Increased flow in the distal nephron induces K secretion through the large-conductance, calcium-activated K channel (BK), which is primarily expressed in intercalated cells (IC). Since flow also increases ATP release from IC, we hypothesized that purinergic signaling has a role in shear stress (τ; 1...

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Detalles Bibliográficos
Autores principales: Holtzclaw, J. David, Cornelius, Ryan J., Hatcher, Lori I., Sansom, Steven C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119139/
https://ncbi.nlm.nih.gov/pubmed/21454249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00112.2011
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