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Real-time dynamic movement of caveolin-1 during smooth muscle contraction of human colon and aged rat colon transfected with caveolin-1 cDNA

Caveolin-1 (cav-1) plays a key role in PKC-α and RhoA signaling pathways during acetylcholine (ACh)-induced contraction of colonic smooth muscle cells (CSMC). Aged rat CSMC showed sluggish contractility, concomitant with reduced expression of cav-1 with an associated reduction in activation of PKC-α...

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Bibliografische gegevens
Hoofdauteurs: Somara, Sita, Bashllari, Daniela, Gilmont, Robert R., Bitar, Khalil N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119117/
https://ncbi.nlm.nih.gov/pubmed/21372166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00301.2010
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