Increases in plasma trans-EETs and blood pressure reduction in spontaneously hypertensive rats

Epoxyeicosatrienoic acids (EETs) are vasodilator, natriuretic, and antiinflammatory lipid mediators. Both cis- and trans-EETs are stored in phospholipids and in red blood cells (RBCs) in the circulation; the maximal velocity (V(max)) of trans-EET hydrolysis by soluble epoxide hydrolase (sEH) is thre...

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Detalhes bibliográficos
Main Authors: Jiang, Houli, Quilley, John, Doumad, Anabel B., Zhu, Angela G., Falck, John R., Hammock, Bruce D., Stier, Charles T., Carroll, Mairead A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119086/
https://ncbi.nlm.nih.gov/pubmed/21398593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01267.2010
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