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Pharmacological Blockade of Serotonin 5-HT(7) Receptor Reverses Working Memory Deficits in Rats by Normalizing Cortical Glutamate Neurotransmission
The role of 5-HT(7) receptor has been demonstrated in various animal models of mood disorders; however its function in cognition remains largely speculative. This study evaluates the effects of SB-269970, a selective 5-HT(7) antagonist, in a translational model of working memory deficit and investig...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119073/ https://ncbi.nlm.nih.gov/pubmed/21701689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020210 |
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