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Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation

Demyelination occurs in multiple inherited mitochondrial diseases. We studied which genes were induced as a consequence of differentiation in rodent and human oligodendroglia. Cholesterol, myelin and mitochondrial genes were significantly increased with oligodendroglial differentiation. Mitochondria...

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Bibliografski detalji
Glavni autori: Schoenfeld, Robert, Wong, Alice, Silva, Jillian, Li, Ming, Itoh, Aki, Horiuchi, Makoto, Itoh, Takayuki, Pleasure, David, Cortopassi, Gino
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119038/
https://ncbi.nlm.nih.gov/pubmed/20005986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2009.12.141
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