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An important role of a pyrethroid-sensing residue F1519 in the action of the N-alkylamide insecticide BTG 502 on the cockroach sodium channel

Deltamethrin, a pyrethroid insecticide, and BTG 502, an alkylamide insecticide, target voltage-gated sodium channels. Deltamethrin binds to a unique receptor site and causes prolonged opening of sodium channels by inhibiting deactivation and inactivation. Previous (22)Na(+) influx and receptor bindi...

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Detalhes bibliográficos
Main Authors: Du, Yuzhe, Khambay, Bhupinder, Dong, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118982/
https://ncbi.nlm.nih.gov/pubmed/21426938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2011.03.005
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