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Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability
BACKGROUND: Amplification of 3q26 is one of the most frequent genetic alterations in many human malignancies. Recently, we isolated a novel oncogene eIF-5A2 within the 3q26 region. Functional study has demonstrated the oncogenic role of eIF-5A2 in the initiation and progression of human cancers. In...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118894/ https://ncbi.nlm.nih.gov/pubmed/21612665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-199 |
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