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Sustained systemic delivery of green tea polyphenols by polymeric implants significantly diminishes benzo[a]pyrene-induced DNA adducts

The polyphenolics in green tea are believed to be the bioactive components. However, poor bioavailability following ingestion limits their efficacy in vivo. In this study, polyphenon E (poly E), a standardized green tea extract, was administered by sustained-release polycaprolactone implants (two, 2...

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Detalhes bibliográficos
Main Authors: Cao, Pengxiao, Vadhanam, Manicka V., Spencer, Wendy A., Cai, Jian, Gupta, Ramesh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118863/
https://ncbi.nlm.nih.gov/pubmed/21574630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2000625
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