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Enhanced activity of punicalagin delivered via polymeric implants against benzo[a]pyrene-induced DNA adducts
We investigated the effect of punicalagin (PC) on benzo[a]pyrene (BP)-induced DNA adducts in vitro and in vivo. Incubation of BP (1 μM) with rat liver microsomes, appropriate co-factors and DNA in the presence of vehicle or punicalagin (1–40 μM) showed dose-dependent inhibition of the resultant DNA...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354568/ https://ncbi.nlm.nih.gov/pubmed/22234049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2011.12.022 |
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