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Hypoxia inhibits induction of aryl hydrocarbon receptor activity in topminnow hepatocarcinoma cells in an ARNT-dependent manner

Hypoxic events often occur in waters contaminated with toxic chemicals, including agonists of the aryl hydrocarbon receptor (AhR). HIF-1α, the mediator of cellular responses to hypoxia, shares a dimerization partner (ARNT) with AhR and reciprocal crosstalk may occur. Studies addressing AhR/hypoxia c...

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Bibliografiska uppgifter
Huvudupphovsmän: Fleming, Carrie R., Billiard, Sonya M., Di Giulio, Richard T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118667/
https://ncbi.nlm.nih.gov/pubmed/19539049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpc.2009.06.003
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