Effect of site-specific DNA methylation and mutagenesis on recognition by methylated DNA-binding protein from human placenta.
Methylated DNA-binding protein (MDBP) from human placenta is the first protein shown to bind specifically to certain DNA sequences only when they are methylated at cytosine residues. Among the sites recognized by MDBP is pB site 1, a pBR322-derived sequence which has a high affinity for MDBP when me...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1986
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3537958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.21.8387 |
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