Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats

Calorie restriction [CR; ∼65% of ad libitum (AL) intake] improves insulin-stimulated glucose uptake (GU) and Akt phosphorylation in skeletal muscle. We aimed to elucidate the effects of CR on 1) processes that regulate Akt phosphorylation [insulin receptor (IR) tyrosine phosphorylation, IR substrate...

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Main Authors: Sharma, Naveen, Arias, Edward B., Bhat, Abhijit D., Sequea, Donel A., Ho, Steve, Croff, Kelsey K., Sajan, Mini P., Farese, Robert V., Cartee, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118592/
https://ncbi.nlm.nih.gov/pubmed/21386065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00659.2010
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