Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms

The t(4;14) translocation in multiple myeloma (MM) simultaneously dysregulates two apparent oncogenes: fibroblast growth factor receptor 3 (FGFR3) controlled by the 3′ immunoglobulin heavy chain enhancer on der(14) and MMSET controlled by the intronic Eμ enhancer on der(4). Although all MM tumors an...

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Bibliographic Details
Main Authors:	Zingone, A, Cultraro, CM, Shin, D-M, Bean, CM, Morse, HC, Janz, S, Kuehl, WM
Format:	Artigo
Language:	Inglês
Published:	2010
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3118571/ https://ncbi.nlm.nih.gov/pubmed/20393505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.50
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Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms

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