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Activation of the Stress Protein Response Inhibits the STAT1 Signaling Pathway and iNOS function in Alveolar Macrophages: Role of Hsp90 and Hsp70
Activation of the stress protein response (SPR) inhibits iNOS-dependent release of NO from alveolar macrophages by blocking the activation of the STAT1 pathway in response to IFN-γ, a major cytokine present in the airspace of patients with acute lung injury. Inhibition of STAT1 phosphorylation after...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118552/ https://ncbi.nlm.nih.gov/pubmed/20388761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2008.101139 |
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