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Insights into Alzheimer disease pathogenesis from studies in transgenic animal models
Alzheimer disease is the most common cause of dementia among the elderly, accounting for ∼60-70% of all cases of dementia. The neuropathological hallmarks of Alzheimer disease are senile plaques (mainly containing β-amyloid peptide derived from amyloid precursor protein) and neurofibrillary tangles...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118437/ https://ncbi.nlm.nih.gov/pubmed/21779722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1807-59322011001300006 |
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