Insights into Alzheimer disease pathogenesis from studies in transgenic animal models

Alzheimer disease is the most common cause of dementia among the elderly, accounting for ∼60-70% of all cases of dementia. The neuropathological hallmarks of Alzheimer disease are senile plaques (mainly containing β-amyloid peptide derived from amyloid precursor protein) and neurofibrillary tangles...

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Bibliographic Details
Main Authors: Schaeffer, Evelin L, Figueiró, Micheli, Gattaz, Wagner F
Format: Artigo
Language:Inglês
Published: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Subjects:
Editorial
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118437/
https://ncbi.nlm.nih.gov/pubmed/21779722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1807-59322011001300006
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