G-Protein βγ-Complex Is Crucial for Efficient Signal Amplification in Vision

A fundamental question of cell signaling biology is how faint external signals produce robust physiological responses. One universal mechanism relies on signal amplification via intracellular cascades mediated by heterotrimeric G-proteins. This high amplification system allows retinal rod photorecep...

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Main Authors: Kolesnikov, Alexander V., Rikimaru, Loryn, Hennig, Anne K., Lukasiewicz, Peter D., Fliesler, Steven J., Govardovskii, Victor I., Kefalov, Vladimir J., Kisselev, Oleg G.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118088/
https://ncbi.nlm.nih.gov/pubmed/21632928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0174-11.2011
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