Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors

PURPOSE: MET-signaling has been suggested a potential role in malignant peripheral nerve sheath tumors (MPNSTs). Here, MET function and blockade were preclinically assessed. EXPERIMENTAL DESIGN: Expression levels of MET, its ligand HGF, and phosphorylated MET (pMET) were examined in a clinically ann...

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Detalhes bibliográficos
Main Authors: Torres, Keila E., Zhu, Quan-Sheng, Bill, Katelynn, Lopez, Gonzalo, Ghadimi, Markus P., Xie, Xianbiao, Young, Eric D., Liu, Juehui, Nguyen, Theresa, Bolshakov, Svetlana, Belousov, Roman, Wang, Suizhau, Lahat, Guy, Liu, Jun, Hernandez, Belinda, Lazar, Alexander J., Lev, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117912/
https://ncbi.nlm.nih.gov/pubmed/21540237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0193
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