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Characterization of HCV Interactions with Toll-Like Receptors and RIG-I in Liver Cells

BACKGROUND AND AIM: The aim of this study was to examine the mechanisms of IFN induction and viral escape. In order to accomplish the goal we compared our new hepatoma cell line LH86, which has intact TLR3 and RIG-I expression and responds to HCV by inducing IFN, with Huh7.5 cells which lack those f...

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Библиографические подробности
Главные авторы: Eksioglu, Erika A., Zhu, Haizhen, Bayouth, Lilly, Bess, Jennifer, Liu, Hong-yan, Nelson, David R., Liu, Chen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117876/
https://ncbi.nlm.nih.gov/pubmed/21695051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021186
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