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Pharmacological characterization of LPS and opioid interactions at the toll-like receptor 4
BACKGROUND AND PURPOSE: Previous work in our laboratory showed opioid agents inhibit cytokine expression in astrocytes. Recently, Watkins and colleagues hypothesized that opioid agonists activate toll-like receptor 4 (TLR4) signalling, which leads to neuroinflammation. To test this hypothesis, we ch...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596647/ https://ncbi.nlm.nih.gov/pubmed/23083095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12028 |
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