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The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the Malaria parasite Plasmodium falciparum

Plasmodium falciparum, the major causative agent of human malaria contains three separate genomes. The apicoplast, an intracellular organelle contains a ∼35kb circular DNA genome of unusually high A/T content (>86%) that is replicated by the nuclear encoded replication complex Pfprex. Herein, we...

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Bibliografski detalji
Glavni autori: Kennedy, Scott R., Chen, Cheng-Yao, Schmitt, Michael W., Bower, Cole N., Loeb, Lawrence A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117635/
https://ncbi.nlm.nih.gov/pubmed/21570407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.071
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