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The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the Malaria parasite Plasmodium falciparum
Plasmodium falciparum, the major causative agent of human malaria contains three separate genomes. The apicoplast, an intracellular organelle contains a ∼35kb circular DNA genome of unusually high A/T content (>86%) that is replicated by the nuclear encoded replication complex Pfprex. Herein, we...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117635/ https://ncbi.nlm.nih.gov/pubmed/21570407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.071 |
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