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Selection of template initiation sites and the lengths of RNA primers synthesized by DNA primase are strongly affected by its organization in a multiprotein DNA polymerase alpha complex.

Synthesis of (p)ppRNA-DNA chains by purified HeLa cell DNA primase-DNA polymerase alpha (pol alpha-primase) was compared with those synthesized by a multiprotein form of DNA polymerase alpha (pol alpha 2) using unique single-stranded DNA templates containing the origin of replication for simian viru...

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Main Authors: Vishwanatha, J K, Yamaguchi, M, DePamphilis, M L, Baril, E F
Formato: Artigo
Idioma:Inglês
Publicado: 1986
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC311753/
https://ncbi.nlm.nih.gov/pubmed/2429260
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