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Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms
Secondary metabolites from microorganisms have a broad spectrum of applications, particularly in therapeutics. The growing number of sequenced microbial genomes has revealed a remarkably large number of natural product biosynthetic clusters for which the products are still unknown. These cryptic clu...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117463/ https://ncbi.nlm.nih.gov/pubmed/21111669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.10.011 |
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