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Identification of a Van der Woude Syndrome mutation in the cleft palate 1 mutant mouse

Mutations in Interferon Regulatory Factor 6 (IRF6) have been identified in two human allelic syndromes with cleft lip and/or palate: Van der Woude (VWS) and Popliteal Pterygia (PPS) Syndromes. Furthermore, common IRF6 haplotypes and single nucleotide polymorphisms (SNP) alleles are strongly associat...

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Detalhes bibliográficos
Main Authors: Stottmann, R.W., Bjork, B.C., Doyle, J.B., Beier, D.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117396/
https://ncbi.nlm.nih.gov/pubmed/20196077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20618
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