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From sets to graphs: towards a realistic enrichment analysis of transcriptomic systems

Motivation: Current gene set enrichment approaches do not take interactions and associations between set members into account. Mutual activation and inhibition causing positive and negative correlation among set members are thus neglected. As a consequence, inconsistent regulations and contextless e...

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Autores principales: Geistlinger, Ludwig, Csaba, Gergely, Küffner, Robert, Mulder, Nicola, Zimmer, Ralf
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117393/
https://ncbi.nlm.nih.gov/pubmed/21685094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr228
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