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From sets to graphs: towards a realistic enrichment analysis of transcriptomic systems

Motivation: Current gene set enrichment approaches do not take interactions and associations between set members into account. Mutual activation and inhibition causing positive and negative correlation among set members are thus neglected. As a consequence, inconsistent regulations and contextless e...

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Main Authors: Geistlinger, Ludwig, Csaba, Gergely, Küffner, Robert, Mulder, Nicola, Zimmer, Ralf
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117393/
https://ncbi.nlm.nih.gov/pubmed/21685094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr228
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