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Small sets of interacting proteins suggest functional linkage mechanisms via Bayesian analogical reasoning

Motivation: Proteins and protein complexes coordinate their activity to execute cellular functions. In a number of experimental settings, including synthetic genetic arrays, genetic perturbations and RNAi screens, scientists identify a small set of protein interactions of interest. A working hypothe...

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Detalhes bibliográficos
Main Authors: Airoldi, Edoardo M., Heller, Katherine A., Silva, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117334/
https://ncbi.nlm.nih.gov/pubmed/21685095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr236
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