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MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck

BACKGROUND: The overall 5-year survival rate of approximately 60% for head and neck cancer patients has remained essentially unchanged over the past 30 years. MicroRNA-137 (miR-137) plays an essential role in cell cycle control at the G1/S phase checkpoint. However, aberrant miR-137 promoter methyla...

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Bibliografski detalji
Glavni autori: Langevin, Scott M., Stone, Roslyn A., Bunker, Clareann H., Lyons-Weiler, Maureen A., LaFramboise, William A., Kelly, Lori, Seethala, Raja R., Grandis, Jennifer R., Sobol, Robert W., Taioli, Emanuela, PhD, MD
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117118/
https://ncbi.nlm.nih.gov/pubmed/21425146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25689
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