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Determination of spatial and temporal distribution of microglia by 230nm-high-resolution, high-throughput automated analysis reveals different amyloid plaque populations in an APP/PS1 mouse model of Alzheimer’s disease

One early and prominent pathologic feature of Alzheimer’s disease (AD) is the appearance of activated microglia in the vicinity of developing β-amyloid deposits. However, the precise role of microglia during the course of AD is still under discussion. Microglia have been reported to degrade and clea...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Scheffler, Katja, Stenzel, Jan, Krohn, Markus, Lange, Cathleen, Hofrichter, Jacqueline, Schumacher, Toni, Brüning, Thomas, Plath, Anne-Sophie, Walker, Lary, Pahnke, Jens
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117051/
https://ncbi.nlm.nih.gov/pubmed/21244350
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