A Phase I Study of Zoledronic Acid and Low Dose Cyclophosphamide in Recurrent/Refractory Neuroblastoma: A New Approaches to Neuroblastoma Therapy (NANT) Study

BACKGROUND: Zoledronic acid, a bisphosphonate, delays progression of bone metastases in adult malignancies. Bone is a common metastatic site of advanced neuroblastoma. We previously reported efficacy of zoledronic acid in a murine model of neuroblastoma bone invasion prompting this Phase I trial of...

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Detalhes bibliográficos
Main Authors: Russell, Heidi V., Groshen, Susan G., Ara, Tasnim, DeClerck, Yves A., Hawkins, Randy, Jackson, Hollie A., Daldrup-Link, Heike E., Marachelian, Araz, Skerjanec, Andrej, Park, Julie R., Katzenstein, Howard, Matthay, Katherine K., Blaney, Susan M., Villablanca, Judith G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117015/
https://ncbi.nlm.nih.gov/pubmed/21671363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.22821
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