M402, a Novel Heparan Sulfate Mimetic, Targets Multiple Pathways Implicated in Tumor Progression and Metastasis

Heparan sulfate proteoglycans (HSPGs) play a key role in shaping the tumor microenvironment by presenting growth factors, cytokines, and other soluble factors that are critical for host cell recruitment and activation, as well as promoting tumor progression, metastasis, and survival. M402 is a ratio...

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Main Authors: Zhou, He, Roy, Sucharita, Cochran, Edward, Zouaoui, Radouane, Chu, Chia Lin, Duffner, Jay, Zhao, Ganlin, Smith, Sean, Galcheva-Gargova, Zoya, Karlgren, Juliane, Dussault, Nancy, Kwan, Rain Y. Q., Moy, Erick, Barnes, Marishka, Long, Alison, Honan, Chris, Qi, Yi Wei, Shriver, Zachary, Ganguly, Tanmoy, Schultes, Birgit, Venkataraman, Ganesh, Kishimoto, Takashi Kei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116871/
https://ncbi.nlm.nih.gov/pubmed/21698156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021106
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