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Dynamics of Antibiotic Resistant Mycobacterium tuberculosis during Long-Term Infection and Antibiotic Treatment

For an infecting bacterium the human body provides several potential ecological niches with both internally (e.g. host immunity) and externally (e.g. antibiotic use) imposed growth restrictions that are expected to drive adaptive evolution in the bacterium, including the development of antibiotic re...

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Detalhes bibliográficos
Main Authors: Mariam, Solomon H., Werngren, Jim, Aronsson, Joakim, Hoffner, Sven, Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116863/
https://ncbi.nlm.nih.gov/pubmed/21698208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021147
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