Cten Is Targeted by Kras Signalling to Regulate Cell Motility in the Colon and Pancreas

CTEN/TNS4 is an oncogene in colorectal cancer (CRC) which enhances cell motility although the mechanism of Cten regulation is unknown. We found an association between high Cten expression and KRAS/BRAF mutation in a series of CRC cell lines (p = 0.03) and hypothesised that Kras may regulate Cten. To...

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Detalhes bibliográficos
Main Authors: Al-Ghamdi, Saleh, Albasri, Abdulkader, Cachat, Julien, Ibrahem, Salih, Muhammad, Belal A., Jackson, Darryl, Nateri, Abdolrahman S., Kindle, Karin B., Ilyas, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116852/
https://ncbi.nlm.nih.gov/pubmed/21698197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020919
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