Predicting Protein Folds with Fold-Specific PSSM Libraries

Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies. Herein, we outline an effective method for fold recognition using sets of PSSMs, each of which is constructed for different protein folds. Our analyses demonstrate that FSL (Fold-specific Position S...

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Detalhes bibliográficos
Main Authors: Hong, Yoojin, Chintapalli, Sree Vamsee, Ko, Kyung Dae, Bhardwaj, Gaurav, Zhang, Zhenhai, van Rossum, Damian, Patterson, Randen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116844/
https://ncbi.nlm.nih.gov/pubmed/21698189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020557
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