High Affinity Nanobodies against the Trypanosome brucei VSG Are Potent Trypanolytic Agents that Block Endocytosis

The African trypanosome Trypanosoma brucei, which persists within the bloodstream of the mammalian host, has evolved potent mechanisms for immune evasion. Specifically, antigenic variation of the variant-specific surface glycoprotein (VSG) and a highly active endocytosis and recycling of the surface...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Stijlemans, Benoît, Caljon, Guy, Natesan, Senthil Kumar A., Saerens, Dirk, Conrath, Katja, Pérez-Morga, David, Skepper, Jeremy N., Nikolaou, Alexandros, Brys, Lea, Pays, Etienne, Magez, Stefan, Field, Mark C., De Baetselier, Patrick, Muyldermans, Serge
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116811/
https://ncbi.nlm.nih.gov/pubmed/21698216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002072
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items