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A distinctive role for focal adhesion proteins in three-dimensional cell motility
Focal adhesions are large multi-protein assemblies that form at the basal surface of cells on planar dishes, which mediate cell signaling, force transduction, and adhesion to the substratum. While much is known about focal adhesion components in 2-D systems, their role in migrating cells within a mo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116660/ https://ncbi.nlm.nih.gov/pubmed/20473295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2062 |
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