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Drosophila homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling

Drosophila Homeodomain-interacting protein kinase (Hipk) has been shown to regulate in vivo, the stability of Armadillo, the transcriptional effector of Wingless signaling. The Wingless pathway culminates in the stabilization of Armadillo that, in the absence of signaling, is sequentially phosphoryl...

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Detalhes bibliográficos
Main Authors: Swarup, Sharan, Verheyen, Esther M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116437/
https://ncbi.nlm.nih.gov/pubmed/21628596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017548108
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