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Substance P antagonist (CP-96,345) inhibits HIV-1 replication in human mononuclear phagocytes

Substance P (SP) is a potent modulator of neuroimmunoregulation. We recently reported that human immune cells express SP and its receptor. We have now investigated the possible role that SP and its receptor plays in HIV infection of human mononuclear phagocytes. SP enhanced HIV replication in human...

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Detalhes bibliográficos
Main Authors: Lai, Jian-Ping, Ho, Wen-Zhe, Zhan, Guan-Xia, Yi, Yanjie, Collman, Ronald G., Douglas, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31163/
https://ncbi.nlm.nih.gov/pubmed/11274418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071052298
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