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Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth
The UBE2C oncogene is overexpressed in many types of solid tumours including the lethal castration-resistant prostate cancer (CRPC). The underlying mechanisms causing UBE2C gene overexpression in CRPC are not fully understood. Here, we show that CRPC-specific enhancers drive UBE2C overexpression in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116285/ https://ncbi.nlm.nih.gov/pubmed/21556051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.154 |
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