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Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

The MEF2 factors regulate transcription during cardiac and skeletal myogenesis. MEF2 factors establish skeletal muscle commitment by amplifying and synergizing with MyoD. While phosphorylation is known to regulate MEF2 function, lineage-specific regulation is unknown. Here, we show that phosphorylat...

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Sonraí Bibleagrafaíochta
Main Authors: Al Madhoun, Ashraf Said, Mehta, Virja, Li, Grace, Figeys, Daniel, Wiper-Bergeron, Nadine, Skerjanc, Ilona S
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116284/
https://ncbi.nlm.nih.gov/pubmed/21556048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.153
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