Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C

The MEF2 factors regulate transcription during cardiac and skeletal myogenesis. MEF2 factors establish skeletal muscle commitment by amplifying and synergizing with MyoD. While phosphorylation is known to regulate MEF2 function, lineage-specific regulation is unknown. Here, we show that phosphorylat...

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Main Authors: Al Madhoun, Ashraf Said, Mehta, Virja, Li, Grace, Figeys, Daniel, Wiper-Bergeron, Nadine, Skerjanc, Ilona S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116284/
https://ncbi.nlm.nih.gov/pubmed/21556048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.153
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