Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing

2′-O-methylation of eukaryotic ribosomal RNA (r)RNA, essential for ribosome function, is catalysed by box C/D small nucleolar (sno)RNPs. The RNA components of these complexes (snoRNAs) contain one or two guide sequences, which, through base-pairing, select the rRNA modification site. Adjacent to the...

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Bibliografiske detaljer
Main Authors: van Nues, Robert Willem, Granneman, Sander, Kudla, Grzegorz, Sloan, Katherine Elizabeth, Chicken, Matthew, Tollervey, David, Watkins, Nicholas James
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116282/
https://ncbi.nlm.nih.gov/pubmed/21556049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.148
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