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T-Oligos Inhibit Growth and Induce Apoptosis in Human Ovarian Cancer Cells

Ovarian cancer remains a leading cause of death among women worldwide, and current treatment regimens for advanced disease are inadequate. Oligonucleotides with sequence homology to telomeres (called T-oligos) have been shown to mimic DNA damage responses in cells and induce cytotoxic effects in cer...

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Detalhes bibliográficos
Main Authors: Sarkar, Sibaji, Faller, Douglas V.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116203/
https://ncbi.nlm.nih.gov/pubmed/21281128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2010.0259
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