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Investigations on Inhibitors of Hedgehog Signal Pathway: A Quantitative Structure-Activity Relationship Study

The hedgehog signal pathway is an essential agent in developmental patterning, wherein the local concentration of the Hedgehog morphogens directs cellular differentiation and expansion. Furthermore, the Hedgehog pathway has been implicated in tumor/stromal interaction and cancer stem cell. Nowadays...

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Detalhes bibliográficos
Main Authors: Zhu, Ruixin, Liu, Qi, Tang, Jian, Li, Huiliang, Cao, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116172/
https://ncbi.nlm.nih.gov/pubmed/21686166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12053018
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