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Leukotriene B(4) Mediates Inflammation via TRPV1 in Duct Obstruction-induced Pancreatitis in Rats

OBJECTIVES: We tested the hypothesis that leukotriene B(4) (LTB(4)) mediates pancreatic inflammation in rats via activation of the Transient Receptor Potential Vanilloid 1 (TRPV1). METHODS: LTB(4) or vehicle was administered to adult rats via celiac axis injection following pretreatment with the TRP...

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Detalhes bibliográficos
Main Authors: Vigna, Steven R., Shahid, Rafiq A., Nathan, Jaimie D., McVey, Douglas C., Liddle, Rodger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116062/
https://ncbi.nlm.nih.gov/pubmed/21602738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e318214c8df
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