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Oxidative Stress in the Developing Brain: Effects of Postnatal Glucocorticoid Therapy and Antioxidants in the Rat

In premature infants, glucocorticoids ameliorate chronic lung disease, but have adverse effects on long-term neurological function. Glucocorticoid excess promotes free radical overproduction. We hypothesised that the adverse effects of postnatal glucocorticoid therapy on the developing brain are sec...

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Main Authors: Camm, Emily J., Tijsseling, Deodata, Richter, Hans G., Adler, Alexandra, Hansell, Jeremy A., Derks, Jan B., Cross, Christine M., Giussani, Dino A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115992/
https://ncbi.nlm.nih.gov/pubmed/21698270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021142
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