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Multiple Actions of Spinophilin Regulate Mu Opioid Receptor Function
Spinophilin, a dendritic spine-enriched scaffold protein, modulates synaptic transmission via multiple functions mediated by distinct domains of the protein. Here, we show that spinophilin is a key modulator of opiate action. Knockout of the spinophilin gene causes reduced sensitivity to the analges...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115895/ https://ncbi.nlm.nih.gov/pubmed/18439408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.02.006 |
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